Lead Optimization

ABLINK combines advanced technologies such as AI assistance, reverse mutation, CDR region modification, and phage display to provide high-quality drug molecular optimization projects, including humanization, immunogenicity removal, affinity maturation, bi-specific modification, and more.

Service Projects

Computer designed antibody humanization

antibody humanization based on AI/fully synthetic library screening

Immunogenicity removal of antibodies/bio-enzymes

affinity maturation of antibodies/proteins

Structure guided antibody functional modification  

Antibody Hinge/Fc region engineering

Stability optimization based on AI/fully synthetic library screening

Recycling/Sweeping antibody modification

AI-assisted bi-specific antibody development

Technical Advantages

1. AI-assisted selection of optimizing sites.

2. Provides a variety of novel drug molecule optimization options to meet different needs.